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Her Barrage can be devastating to unprepared groups especially heroes or henchmen who tend to group together. If using heroes, it is wise to flag them apart from each other. Blind works relatively well against the boss.
Might be slow to spawn, try walking around the area of the last eggs in that case.
Trivia
Αράχνη (Arachne) is Greek for spider (Arachnid in English).